Colorado's Tech Companies
The companies building, scaling and shipping product across the state, from pre-seed startups to public industry leaders. Filter by sector, stage or region.
Denver-based technology talent search firm placing engineers and technical leaders — machine-learning engineers, cloud architects, full-stack developers, and DevOps specialists — for companies driving AI adoption and digital transformation.
Senior-led program and project management consultancy delivering M&A integration, enterprise transformations, and complex software implementations, with AI integrated into each engagement.
Medical device company developing an innovative 1726nm laser platform for treating mild to severe inflammatory acne by targeting sebaceous glands.
Mobile app user-acquisition and monetization platform delivering performance marketing and offerwall solutions.
Advanced Energy designs and manufactures precision power conversion, measurement, and control technologies. Its products power semiconductor manufacturing, data centers, industrial production, and medical applications worldwide.
Space mission operations and astrodynamics company that owns and operates NASA's CAPSTONE lunar pathfinder spacecraft, demonstrating cislunar navigation technology in support of the Artemis program. Contract-funded with 100+ employees.
Biotech developing proprietary siRNA and high-throughput formulation technology for next-generation pharmaceuticals and advanced materials.
Neurotechnology company developing haptic feedback devices that create realistic touch sensations through direct nerve stimulation.
Insurance compliance and producer management platform automating licensing, onboarding, and compliance workflows for carriers and agencies.
Specializes in 3D-printed propulsion, test-rocket services, and space exploration hardware for government and commercial space programs.
Helps government agencies and large nonprofits administer guaranteed-income and aid programs efficiently and transparently.
Operates very-low-Earth-orbit (VLEO) imaging satellites delivering 10cm-class commercial imagery and thermal data — Clarity-1 is on orbit today.
Alchemer (formerly SurveyGizmo) is a customer experience and voice-of-the-customer platform that enables organizations to collect, analyze, and act on feedback through advanced survey, workflow automation, and digital feedback tools. Backed by KKR, the company serves enterprises seeking capabilities beyond basic survey tools without the complexity of enterprise suites like Qualtrics.
Medical device company whose FDA-cleared SmartPatch is a non-invasive wearable for remote patient monitoring, tracking metrics like potassium, hemoglobin, heart rate and skin temperature for dialysis and chronic kidney disease patients.
Creator network and media company connecting local sports content creators with brands and audiences across digital platforms.
Innovative solutions for efficient mineral separation and sourcing — enabling cleaner critical-mineral extraction for batteries and electronics.
Embedded finance platform offering accounts, payments, branded cards, and global money transfer for non-bank brands and large enterprises.
Biotechnology company developing small-molecule, GLP-1–based drugs for metabolic disorders and weight loss, founded by former Array BioPharma researchers.
AMP Robotics applies AI, computer vision, and robotics to automate recycling and waste sortation, including a first-of-its-kind AI system to sort municipal solid waste. The company has raised over $266M and in 2024 named Tim Stuart (former Republic Services COO) CEO while founder Matanya Horowitz transitioned to CTO.
Builds software-defined power systems for spacecraft — its WattDot product line combines standardized COTS hardware with configurable software to replace custom-built satellite power management and distribution.
Cryptocurrency and digital asset platform focused on accessible fintech solutions.
Apollo delivers next generation cybersecurity as a service to state, local and mid-enterprise customers. Operationally headquartered in Denver; nominally HQ'd in Dallas.
Biotechnology company developing a high-throughput transcriptomics platform combining nascent RNA sequencing and machine learning to map how chemical compounds influence gene expression.
Arrow Electronics is a Fortune 500 global distributor of electronic components and enterprise computing products and services, serving industrial and commercial users worldwide.
Mobile point-of-sale and operations platform for breweries, taprooms, and hospitality businesses, including payments, online ordering, and loyalty tools. Has raised about $27.9M total, most recently a $21M Series B in June 2021 led by Tribe Capital and Foundry Group.
Artimus Robotics commercializes HASEL artificial muscle technology spun out of CU Boulder, enabling soft, lightweight, and precise actuation for defense, industrial, and underwater applications. The U.S. Navy was an early customer for underwater applications.
Industrial decarbonization company developing electric boiler technology to eliminate fossil fuels from industrial heat processes.
Builds neutral-atom quantum computers; in 2023 was the first to surpass 1,000 qubits. Co-headquartered in Boulder and Berkeley.
Space and cyber software company providing ground systems, SATCOM, mission planning, and DevSecOps solutions for U.S. Space Force and national security customers. Formed in 2024 when Enlightenment Capital merged Boecore (founded 2000), Ascension Engineering, Orbit Logic, and La Jolla Logic; has 400+ employees.
Cloud-native endpoint hardening and patch automation for Windows, macOS, and Linux. Founded by Jay Prassl and Mark Manes; >$150M raised.
Defense-focused robotics company developing modular in-wheel electric drive systems (e.g., the S26 wheel module) that convert structures into unmanned ground vehicles for logistics, reconnaissance, and other military/security applications.
Real estate investment platform providing data, financing, and tools for residential real estate investors to find and fund deals.
Designs and additively manufactures low-cost, expendable jet engines (the Frenzy family) for drones, cruise missiles, and collaborative combat aircraft. Opened a 60,000 sq ft headquarters in Centennial in 2025, employs 200+ people, and won a $29.7M U.S. Air Force contract in April 2026 to qualify the Frenzy 8 engine.
Photonics design and advanced development firm specializing in coherent lidar, stable single-frequency lasers, and laser-based remote sensing for government and aerospace customers. An independent, SBIR-funded small business.
Quantum hardware company developing scalable, magnetically insensitive electro-optic quantum amplifiers for quantum computing readout; the only U.S. commercial producer of quantum-limited amplifiers.
Large-format hybrid metal additive manufacturing company producing big structural parts for space, aerospace, maritime, energy, and heavy equipment customers. Funded primarily through customer revenue and government work, including a $5.4M NASA award for lunar exploration manufacturing.
Bill-pay infrastructure powering payments for financial institutions, fintechs, and billers — modernizing how Americans pay their bills.
Smart firearm safety company developing biometric-enabled handguns that only fire for authorized users.
Small satellite manufacturer and mission services provider building CubeSats, microsats, and spacecraft components for government, commercial, and academic missions. Acquired by Raytheon Technologies (now RTX) in December 2020; operates its Satellite Constellation Factory headquarters in Lafayette plus a Boulder facility.
Builds secure enterprise data-management software for the U.S. government, including the Unified Data Library powering Space Force space-domain awareness.
BoBoRobo (Boulder-Born Robotics) automates the design, validation, and deployment of industrial robotic workcells from English-language prompts using an agentic AI engine. The technology aims to cut integration costs by 50% and reduce time-to-deploy from six months to ten days.
Bolder Industries converts end-of-life tires into recovered carbon black and pyrolysis oil using a proprietary process that uses 90% less CO2, water, and energy than traditional methods. The company operates facilities in Missouri and Indiana and is expanding internationally, with a facility under development at the Port of Antwerp.
AI-native B2B software platform helping businesses automate and streamline operational workflows.
BombBomb is a video messaging platform that enables business professionals in real estate, mortgage, finance, and insurance to record and send personalized video emails, boosting open rates and customer engagement. The platform integrates with Salesforce and HubSpot, serving over 60,000 users across 43 countries.
Animal nutrition company using fermentation biotechnology to produce high-quality meat proteins for pet food without slaughter.
Employee recognition and rewards platform helping companies build engaged, high-performing cultures through peer-to-peer recognition.
Developing Overture, a commercial supersonic airliner. The XB-1 demonstrator broke the sound barrier in January 2025 — the first privately funded jet to do so.
B2B marketplace connecting brands with vetted marketing agencies, streamlining the agency search and procurement process.
AI research helper that produces intelligent, trustworthy financial analysis on any topic for analysts, investors, and corporate strategy teams.
Digital health company providing accessible and affordable healthcare solutions for underserved communities.
HIPAA- and GDPR-compliant blockchain platform for secure health-data exchange and management.
Designs all-electric aircraft, including the eFlyer family, for flight training and regional travel.
Construction-tech company providing pre-engineered, laser-marked cold-formed steel framing kits synced to a digital model, plus software (BYLD Portal) that converts architect plans into code-compliant structures for faster, lower-waste on-site assembly.
Caliola is a woman-owned defense contractor building secure and resilient mission-critical communications solutions, including nuclear command and control (NC3), military SATCOM, modernized HF, and assured PNT. The company ranked #102 on Deloitte's 2024 Technology Fast 500 with 1,178% three-year growth.
Aerospace company developing reusable thermal protection systems (heat shield tiles) for spacecraft, re-entry vehicles and hypersonics using additive manufacturing.
Carbon capture company developing and deploying commercial carbon capture and storage solutions across industrial facilities in the US.
Fintech that helps drivers refinance auto loans and lower car payments — the leading auto-refi marketplace in the U.S.
Biotechnology company developing biocatalytic processes for sustainable chemical manufacturing and green chemistry applications.
Chat-first virtual care platform offering on-demand physician access through health plans and employers. Acquired by Quantum Health in March 2026.
CisLunar Industries is developing Modular Space Foundries that process metal in space, recycling space debris into propellant and manufacturing feedstock. The company has won SpaceWERX SBIR contracts with partners including Astroscale and Colorado State University.
AI-powered cardiac imaging platform that diagnoses heart disease earlier and more accurately by analyzing CT scans for plaque rather than blockages alone.
AI-powered clinical-intelligence platform for digital intake, remote monitoring, and rules-based clinical reasoning.
Cloud security services company helping enterprises protect data and manage risk across cloud environments.
AI-native mobile advertising infrastructure company rebuilding ad monetization for publishers, using LLM agents and secure auction environments to automate ad operations.
AI platform that monitors public meetings and government proceedings to surface relevant insights for organizations.
Network-neutral colocation and interconnection provider operating 45+ data centers across 12 North American markets. Majority-owned by Stonepeak since 2017 (with a $3B equity recapitalization in 2022); closed a $525M asset-backed securitization in July 2025 to fund AI and cloud capacity growth.
Revenue lifecycle management platform delivering CLM, CPQ, and document automation. Originally built on Salesforce; backed by Thoma Bravo and serves thousands of enterprise customers globally.
Manufacturer of engineered technical ceramics and advanced materials for semiconductor, aerospace, medical, and industrial applications.
Copper Labs builds wireless energy monitors that deliver real-time data from existing electric, gas, and water meters, helping utilities accelerate grid modernization and demand-side flexibility without smart meter rollouts. The company raised a $5.5M Series A in 2022.
Biopharmaceutical company developing SRC-3 knock-out regulatory T-cell (Treg) immunotherapies to treat aggressive solid-tumor cancers, based on Baylor College of Medicine research.
Operator of carrier-neutral data centers and interconnection services across major US markets.
Cowboy Clean Fuels produces carbon-negative renewable natural gas using waste agricultural byproducts converted via a biogenic process in deep geologic formations, simultaneously sequestering CO2. Founded by Ryan Waddington, the company closed a $7.5M Series A in 2023 and a ~$13M Series B in 2024.
B2B AI and data platform providing credible, verifiable data intelligence solutions for enterprise decision-making.
AI decision-automation platform for corporate credit management — automating credit reviews, monitoring, and risk recommendations.
Digital medical record retrieval platform combining AI-driven analysis with human expertise to deliver a complete clinical picture for providers, payers, and patients. Founded by Carm Huntress after navigating his mother's medical records; raised an oversubscribed $5.25M seed in 2024.
Vertically integrated AI infrastructure company that builds and operates large-scale data centers powered by clean and stranded energy sources. Valued at $10B+.
First-of-its-kind passwordless authentication platform protecting people and privacy without storing biometric or knowledge-based factors centrally.
Software startup providing open-source software and AI capabilities for national-security systems on classified networks and tactical edge environments.
Franchise operations platform streamlining onboarding, training, and daily task management for franchise businesses.
Defense technology company focused on automating the production of energetics at scale for U.S. defense and allied customers.
App-driven mobile and virtual healthcare platform delivering in-home medical care and hospital-at-home services. In 2025, DispatchHealth merged with Medically Home to become the nation's largest provider of hospital-level care at home, serving 50+ metro areas in partnership with ~40 health systems.
Offers EHR-integrated mobile workflow and voice-powered documentation software that lets physicians dictate notes in real time and streamlines claims for clinics, surgery centers, and hospitals. Has raised about $6.4M to date.
Predictive, generative-AI data platform delivering analytics and insights to K-12 educators by re-imagining school data in a teacher-friendly interface.
CU Boulder spinout making phase-mask optics and software for 3D nanoscale super-resolution imaging, with applications in spatial omics and industrial inspection. Backed by Luminate and seed investment.
AI-powered website builder and small business platform that generates complete websites and business tools in seconds.
Maker of the FRENZ Brainband, a sleep-science wearable plus mobile app that uses neuroscience-driven audio to improve sleep and focus.
Investment platform connecting grant funding opportunities with entrepreneurs and small businesses.
EchoStar provides satellite communications and 5G wireless services through brands including Boost Mobile, Sling TV, and Hughes/HughesNet. The company absorbed DISH Network in a 2024 merger, consolidating its satellite, pay-TV, and wireless operations.
Develops, owns, and operates wholesale hyperscale data center campuses for major cloud and technology companies, entering 2026 with 1.8GW of capacity delivered or under development. Acquired by Partners Group in 2022; completed a $1.9B equity raise in September 2024, bringing committed capital to over $5.9B.
Cloud-native software distribution platform deploying AI in complex industrial environments, enabling manufacturers to activate smart systems and optimize operations.
Low-temperature electrochemical iron refining for green steel; building its first pilot plant in Boulder using renewable electricity instead of coke.
Develops and supplies advanced metal powders and printable alloys (aluminum, nickel, copper, tantalum, tungsten) for metal additive manufacturing, using patented reactive additive manufacturing technology. Raised a $10.2M Series B in January 2022, about $24M total.
Home electrification and heat-pump provider offering technology-enabled efficiency upgrades with integrated rebate processing.
AI-powered consumer-directed benefits administration platform for FSAs, HSAs, and HRAs, serving employers, TPAs, health plans, and financial institutions.
Smart home energy management company making EV charging and home electrification affordable and accessible.
Empower is the second-largest US retirement plan recordkeeper, with approximately $1.8 trillion in assets under administration. A subsidiary of Great-West Lifeco, the company serves more than 19 million customers across workplace retirement plans, IRAs, and wealth management.
Software tools for planning today's energy systems and their transition to a decarbonized future — used by utilities, regulators, and grid operators.
Harnessing engineered microbes to extract critical minerals from low-grade ore — enabling sustainable mining and reducing the carbon cost of the energy transition.
Provides predictive climate-risk analytics for financial market participants, analyzing how the energy transition affects corporate performance, asset values, and credit risk; investors include Societe Generale and Wexford Capital. Secured roughly $10.25M via a Series AA round in November 2025.
AI-driven drug discovery using PRISM, a foundation model trained on >1B small-molecule mass spectra to find naturally occurring molecules for new medicines.
Designs, manufactures, and tests solid rocket motors, black powder, and energetic materials for government and commercial customers; spun out of hobby-rocketry maker Estes Industries in 2021. Through its subsidiary GOEX Industries it is the only American manufacturer of black powder.
Commercial space-weather company operating a dedicated satellite constellation to monitor solar activity, the solar wind, magnetosphere and ionosphere, plus space surveillance/tracking, delivering the data as a service to protect satellites and Earth-based infrastructure.
Vertical SaaS platform for service-commerce industries including home & field services, health services, and fitness & wellness. Publicly traded on Nasdaq (EVCM).
Builds solar electric propulsion systems, Hall-effect thrusters, and power modules for microsatellites, supplying 21 propulsion modules for York Space Systems' SDA Transport Layer satellites. Acquired by Denver-based Voyager Technologies in October 2025.
Makes the Massbox, the first desktop laser ablation laser ionization time-of-flight mass spectrometer (LALI-TOF-MS). Closed a $6M Series A in 2023 and raised additional Series A funding in December 2025, about $11.2M total.
FareHarbor provides booking and business management SaaS for tour, activity, and attraction operators worldwide. The platform handles online reservations, payments, and operational workflows for tens of thousands of suppliers; acquired by Booking Holdings in 2018.
WebAssembly cloud platform enabling developers to build and run serverless applications faster using Wasm components.
Develops HEDscan, the first commercially available non-cryogenic wearable whole-head MEG brain imaging system using optically pumped magnetometer quantum sensors. Funded primarily through NIH/SBIR grants and government contracts; completed phase-2 clinical trials with epilepsy and Parkinson's patients in 2024-2025.
Provides cloud-based phone and unified communications (UCaaS) services for small and mid-size businesses, with 100+ CRM integrations and six straight years on the Inc. 5000. Grew without venture funding and was acquired by Ooma in a roughly $45M cash deal announced in November 2025.
AI-powered sales-enablement platform helping B2B teams craft tailored, account-based business cases and selling documents.
AI-driven growth and marketing platform that automates content generation, creative iteration, and channel-level performance optimization.
Nutrition intelligence company (formerly bitewell) that developed the FoodHealth Score, a 0-10 nutrition metric it licenses across the food ecosystem to power nutrition transparency; pivoted away from its earlier food-as-medicine employer marketplace.
Public safety data analytics platform transforming disconnected law enforcement data into actionable real-time insights for informed decision-making by first responders.
BettrData is an AI and machine-learning data operations company that streamlines end-to-end data management, from processing to activation. The platform incorporates no-code/low-code tools for data professionals to automate workflows across diverse data sources.
U.S. semiconductor equipment and advanced materials company pioneering Atomic Layer Deposition (ALD) technology for AI-era chip manufacturing and defense battery applications. In April 2026 announced a SPAC merger with Archimedes Tech SPAC Partners II to list on NASDAQ as NANO at a $1.2B pre-money valuation; closing targeted for H2 2026.
Spun out of Elementum 3D, Fortius Metals develops next-generation welding wire alloys for large-format metal 3D printing and robotic welding for aerospace and defense. Raised a $5M seed round (roughly $10.4M overall) with investors including AM Ventures and ArcelorMittal.
LLM observability, evaluation, and prompt-management platform helping enterprise product teams build feedback loops to continuously improve generative AI features. Raised a Series A in June 2025 led by Renegade Partners, bringing total funding to roughly $12M. Remains independent and is NOT acquired.
Low-cost live TV streaming service founded by Dish Network alumni, offering 50+ family-friendly channels such as Hallmark, A&E, and Lifetime. Raised only about $3.9M before being acquired by Roku for $185M in a cash deal announced May 2025; continues operating as part of Roku.
AI-backed autism care startup using digital phenotyping technology trained by clinicians to analyze therapeutic sessions and help BCBAs reduce administrative burden.
Leading provider of high-reliability, radiation-hardened electronics for space and national security, including rad-hard components, mission processors, custom ASICs, and RF solutions. Formed in January 2023 when Veritas Capital acquired and rebranded CAES Space Systems (heritage Aeroflex/Cobham Colorado Springs).
Identity resolution SaaS using a patented identity graph and audience insights to enrich contacts for brands, marketers, and ad-tech platforms.
Customer identity and access management (CIAM) for developers — secure, complete, and affordable. Self-host or cloud-deploy in any environment.
Cloud-based healthcare supply-chain platform connecting providers and suppliers for procurement, inventory, and compliance. In January 2026, Veritas Capital agreed to acquire a majority stake, joining existing shareholders Temasek and Warburg Pincus.
Gloo (Nasdaq: GLOO) is a technology platform serving the faith and flourishing ecosystem, providing AI-powered tools that help churches and nonprofits modernize workflows, expand donor reach, and amplify community impact. The platform combines marketing, data, and ministry-focused software to help organizations grow and retain engagement.
Provider of in-flight broadband connectivity for business aviation, headquartered in Broomfield and publicly traded (NASDAQ: GOGO). Completed its acquisition of Satcom Direct in December 2024 for $375M cash plus stock, creating a combined company with roughly $890M in pro forma revenue.
Recommerce marketplace for buying and selling secondhand baby and children's gear, reducing waste in early childhood products.
Market network for government contracting — think AngelList for federal procurement. Aggregates contract intelligence and connects buyers, primes, and resellers.
Public-safety technology company providing AI-powered quality assurance, training, and decision-support tools for 911 emergency communications, law enforcement, and fire/EMS agencies; flagship product CommsCoach automates dispatch evaluations and real-time feedback.
GovTech leader providing digital solutions for federal, state, and local governments — website management, digital communications, online services, and records.
AI-powered, tax-aware equity-compensation planning platform for financial advisors, enabling modeling of stock options, RSUs, ISOs and ESPPs to help clients optimize equity decisions (built on StockOpter logic).
Gravitee is an Agentic API and Event Management platform that enables organizations to securely orchestrate, govern, and observe digital traffic across APIs, real-time event streams, and agentic AI systems. Founded by a team of open-source pioneers, it has raised over $125M and serves enterprises globally.
Orion by Gravity is an AI analyst that performs proactive, deep research on enterprise data — always-on, accurate, and built for analysts.
Great Sky is building Superconducting Optoelectronic Networks (SOENs), a brain-inspired computing architecture that integrates superconducting circuits operating at cryogenic temperatures with photonic links capable of transmitting single-photon signals to address compute and communication bottlenecks at AI scale. The technology is based on 12 years of NIST research producing 23 peer-reviewed publications and 8 patents. Founded by four former NIST researchers.
Home-staging startup that stages 'shoppable homes' for sale and sells the furniture and decor online, supporting independent and local makers.
Education benefits platform connecting frontline employees at Walmart, Disney, Target and others with degree and skilling programs. Co-founded by Rachel Romer; >$700M raised.
Builds ultra-high-power-density integrated electric motor drives (HPDM line) for aerospace, defense, and marine electrification. Closed an oversubscribed $20M Series A in August 2024 led by Infinite Capital with participation from Lockheed Martin Ventures, roughly $28.7M total.
Women's ski apparel brand designing technical outerwear that transitions seamlessly from mountain to après ski.
Agtech platform using solar-powered smart collars for virtual fencing and AI-driven herd management.
Wearable technology that uses AI and haptic feedback to support communication for people who are blind, deafblind, or speech-impaired.
Unified runtime platform consolidating data, logic, and application functions into a single system for full-stack AI-powered application development (formerly HarperDB).
Online interior design platform and home brand group founded by Lee Mayer, pairing customers with designers and selling furnishings; has acquired The Inside, Interior Define, and The Citizenry while expanding into brick-and-mortar retail. Has raised $57.8M total, most recently a $32M Series C led by Foundry Group.
Mobile app providing real-time captioning, speech-to-text, and ASL tools for Deaf and Hard-of-Hearing communities.
Client-engagement platform delivering homeowner financial intelligence to mortgage and real estate professionals. RiNo-based fintech-adjacent SaaS.
Space and defense robotics (Mars rover sampling tools, lunar drills); acquired by Blue Origin in 2022 with a major Colorado facility. Originally founded in New York City in 1983; Colorado operations established later.
Northern Colorado fusion company developing a capital-efficient path to fusion energy by combining two low-capital fusion approaches with advanced superconducting magnets, initially targeting a high-flux neutron source for aerospace materials and electronics.
Business travel lodging platform providing companies with discounted hotel rates and streamlined travel management.
Veterinary workforce platform: a marketplace and software for hiring, job search, and relief-shift coverage that helps vet clinics recruit and retain veterinary professionals. Acquired Relief Rover in 2023.
Field-service management software helping home-service businesses handle scheduling, dispatching, invoicing, and payments.
Distributed energy company deploying mini-grid systems powered by biomass and solar to electrify rural communities in Asia and Africa.
Marketplace and operating system for AI infrastructure, connecting developers and enterprises to GPUs pooled from data centers worldwide via its Brokkr AI Factory Operating System and Confidential Metal bare-metal offering.
Ibotta operates a performance marketing platform that delivers digital promotions to over 200 million consumers via the Ibotta Performance Network (IPN), a network of publishers including Walmart, Family Dollar, and Dollar General. Founded by Bryan Leach, it pioneered a pay-per-sale model where CPG brands only pay when their campaigns drive sales. Its April 2024 IPO was the largest tech IPO in Colorado history.
Athlete marketing platform connecting brands with college and professional athletes for NIL deals and sponsorship opportunities.
Payments enablement platform helping software companies launch and manage embedded payment solutions for their customers.
Quantum information platform spun out of CU Boulder JILA; commercializing cold-atom quantum computing, quantum sensing, and quantum networking. Went public on NYSE in February 2026.
Enterprise AI platform helping large organizations rapidly prototype, test, and deploy AI-powered products and experiences.
AI-powered voice control and automation platform for luxury smart homes.
Boulder-based maker of ultra-concentrated coffee and espresso; one tablespoon of concentrate makes a full cup of hot or iced coffee. Sold direct-to-consumer.
Open Directory Platform unifying identity, device, and access management for IT teams across Windows, macOS, and Linux. Unicorn-valued; ~960 employees.
Platform transforming whole-genome sequencing into personalized care and navigation for patients with rare and complex conditions.
Distributed inference and AI orchestration platform letting enterprises run GenAI workloads across cloud, core data center, and edge environments.
Karman+ is building autonomous spacecraft to mine near-Earth asteroids for water and metals to fuel the in-space economy. Founded by serial entrepreneur Teun van den Dries (formerly of GeoPhy) and Daynan Crull, the company aims to demonstrate its first mission in 2027.
Provides autonomous space traffic coordination and collision-avoidance software for satellite operators through its Pathfinder spaceflight safety platform. Has raised about $12M across seed rounds, most recently a $7M seed extension in September 2023 led by Space Capital.
Commercial solar energy company developing and managing solar installations for businesses, municipalities, and nonprofits.
Founded by physicists Henry Kapteyn and Margaret Murnane, KMLabs makes ultrafast femtosecond-to-attosecond laser systems and coherent EUV/soft X-ray sources. It raised a $7.2M Series A led by Intel Capital in 2016 and a $12.2M equity round in 2018.
Geologic (natural) hydrogen exploration and extraction; raised a ~$246M Series B led by Khosla Ventures with backing from Breakthrough Energy Ventures and Amazon's Climate Pledge Fund.
KPA is an EHS compliance and workforce safety company serving the automotive industry, helping dealerships, shops, and automotive-adjacent businesses achieve regulatory compliance, manage risk, and protect employees through compliance software, expert on-site consulting, and an award-winning training library. In January 2026 KPA refocused exclusively on automotive and spun off its non-automotive safety software (Flex and Risk Management Center) into a separate company, Novara, which serves high-risk industries such as manufacturing, construction, utilities, and oil and gas.
On-demand labor marketplace connecting businesses with vetted workers for moving, delivery, and general labor tasks.
Cryptographic state-proof infrastructure enabling cross-chain interoperability through verifiable proofs rather than trusted intermediaries.
Real-time AI translation software that lets customer-support teams communicate with users in 150+ languages.
AI-powered clinical decision-support for chronic pelvic pain and endometriosis, embedded natively in EHRs.
Customer onboarding and implementation platform unifying forms, documents, tasks, and client communication for B2B software teams.
Space logistics company building mass-manufacturable, low-cost launch solutions using its proprietary Dual Mode Rocket Engine (DMRE) for responsive access to space and point-to-point delivery.
LeTau Robotics develops AI foundation models that teach robots human-like dexterity with 100x less training data, enabling rapid deployment for complex manipulation across manufacturing, logistics, and labs. The company was selected for CU Boulder's 2026 Ascent Deep Tech Accelerator cohort.
Electric RV company building aerodynamic, all-electric travel trailers for the next generation of sustainable adventure travel.
AI-native pre-construction software platform that reviews architectural and engineering documents for constructability, quality, safety, and compliance issues for developers and contractors.
Develops proprietary electro-optic polymer materials and modulators for high-speed silicon photonics in AI data centers and telecom.
Online pain-care platform delivering integrative, personalized, science-based programs led by clinicians who specialize in chronic pain management.
Develops resilient GPS/GNSS positioning technology for aerospace and defense applications.
CU Boulder spinout providing continuous laser-based methane emissions monitoring for oil and gas operations. Raised a $22M Series A in December 2022, then finalized a $162.4M DOE loan guarantee in October 2024 to expand its nationwide methane monitoring network.
AI-powered talent-intelligence platform unifying sourcing, CRM, ATS, and recruiting AI agents.
Denver-based cognitive performance company building sensory-immersion products (e.g. MindGym) that blend technology and neuroscience to train mental skills; serves U.S. military (Air Force, Navy), aviation, research, and corporate wellness customers.
Builds advanced spacecraft and rovers for lunar and Mars missions, including the MAPP rover landing on the Moon as part of NASA CLPS.
Lux Aeterna is building fully reusable satellites equipped with heat shields and parachutes for safe atmospheric reentry and landing, aiming to fundamentally change satellite economics. Founded by SpaceX, Amazon Kuiper, and Loft Orbital veteran Brian Taylor, the company plans a first demo mission with its Delphi prototype in 2027.
Builds edge-AI computer-vision hardware and software, including the OAK camera line.
AI platform for educators that automates lesson planning, IEPs, feedback, and differentiation — used by millions of teachers across schools and districts.
Clean energy company developing innovative solutions for distributed energy storage and grid management.
Mana Battery develops anode-free sodium-ion battery cells and a proprietary fluorine-free, fire-extinguishing electrolyte that delivers higher energy density than LFP lithium-ion at roughly half the cost, targeting defense, grid storage, and low-cost EV applications. Spun out of CU Boulder professor Chunmei Ban's lab, the team includes alumni from Tesla, Solid Power, and SiILion. Solid Power founder Doug Campbell serves as an independent director.
AI platform for proactive mental health ('Mental Health You Can See'); analyzes text-based content using the OCEAN framework to surface daily personality insights and flag mental-health changes, primarily for colleges and universities to mitigate student-wellbeing risk.
Digital mortgage platform for community lenders that has originated $7B+ in loans — founded after the founders' frustrating personal homebuying experience.
Builds dilution refrigerators (the Icebox) that keep quantum chips at near absolute zero, enabling more practical quantum computing deployments.
Whole-food meat alternative brand making mycelium-based (mushroom-root) steaks, cutlets, and jerky. Original operator Emergy, Inc. entered an Assignment for the Benefit of Creditors in 2025; the Meati Foods brand and assets were acquired by Meati Holdings, Inc. and are being restructured for a 2026 relaunch.
Mersive develops Solstice, a wireless content-sharing and collaboration platform deployed in over 300,000 meeting rooms, huddle spaces, and classrooms worldwide. Founded by Christopher Jaynes, the company was acquired by OpenGate Capital in 2017 and continues to expand its collaboration suite for hybrid work.
Quantum sensor manufacturing company providing volume manufacturing of integrable chip-scale quantum sensing technology for PNT and timing.
InsurTech platform delivering a modern insurance experience for sales partners and policyholders in commercial lines.
Open-source payments infrastructure platform providing developer-friendly APIs for moving, storing, and managing money.
AI-native sales enablement platform that surfaces relevant content and insights for revenue teams during live customer conversations.
Developer of AI-powered autonomous mobile robots (AMRs) that automate trailer and container loading and unloading for warehouses and distribution centers.
NetSuite-native accounting software built by former Big 4 auditors enabling automated lease compliance, fixed assets management, and loan accounting for financial teams.
Enterprise cloud development platform with no-code applications for ERP-class workloads. Founded by serial Oracle/PeopleSoft executives.
Builds developer tools for the U.S. transmission and interconnection process — helping renewable developers navigate queue dynamics and grid constraints.
Nitric is an open-source cloud-aware framework that unites backend and infrastructure code, automatically generating Terraform or Pulumi deployments from application code across AWS, GCP, and Azure. The platform abstracts cloud primitives like databases, compute, storage, and messaging so developers can ship in their preferred language without writing IaC by hand. CEO Steve Demchuk previously held roles at IBM and Rally Software.
AI-powered, text-based support platform that connects neurodivergent individuals and their families with their entire support team in one unified ecosystem. Built by a neurodivergent team for neurodivergent users.
Nomad is a proptech platform offering guaranteed rent and property management services to small landlords in the single-family rental market. Founded by Opendoor and Twilio alums Matt Thelen and PJ O'Neil, the company helps DIY landlords reduce vacancy risk and operational burden.
Global Palantir partner specializing in building AI software on Foundry and AIP for defense, government, and large commercial enterprises.
Privately held defense technology company developing advanced tracking, sensor fusion, and data fusion software for air, missile, and space defense. In January 2025 it divested its radar hardware and command-and-control businesses to Anduril Industries, refocusing on its core software.
Develops remote-sensing software (ENVI, IDL) for geospatial imagery analysis; a subsidiary of NV5 Global.
nVoq provides AI-powered clinical documentation and speech recognition solutions purpose-built for healthcare, enabling physicians and clinicians to convert spoken words into structured documentation within seconds. The company specializes in medically trained voice technology integrated into EHR platforms serving home health, hospice, and skilled nursing providers.
NIST spinout building fiber-coupled nonlinear nanophotonic devices for supercontinuum generation, frequency comb stabilization, and atomic clocks. Funded by SBIR/STTR grants from NASA, DARPA, USAF, ONR, and a NIST CHIPS award; won the 2024 Colorado Governor's Award for High-Impact Research.
Technology and finance platform for distributed renewable energy companies — software for project planning, portfolio management, and financing.
Ojje is an AI-powered adaptive literacy platform for K-12 that generates personalized, interactive children's stories where each child can star in the narrative, with every story available across 15 reading levels in English, Spanish, and other languages. Features include read-aloud support, synchronized word highlighting, dyslexia accessibility, and Science of Reading decodables. Founded by Adrian Chernoff (ex-Disney Imagineer, NASA, GM) and Nathan Fennel (ex-Meta, Google, Uber, Snap).
Fintech platform connecting traditional banks with the tokenized financial system — bridging fiat rails and blockchain settlement.
AI-driven precision oncology company spun out of argenx and the University of Colorado Anschutz Medical Campus, advancing cusatuzumab for newly diagnosed AML. Raised a $30M Series A in 2023 and a Series A extension in November 2024 (about $44M total) to fund its Phase 2 trial.
Supply chain sustainability platform helping companies measure, manage, and reduce Scope 3 greenhouse gas emissions.
End-to-end cybersecurity advisory and managed-services provider with ~2,300 employees serving Fortune 500 enterprises across the threat lifecycle.
Developer of in-space refueling infrastructure ('Gas Stations in Space'), including the flight-qualified RAFTI fueling port and planned hydrazine fuel delivery to GEO satellites for the U.S. Space Force. Raised a $20M Series B led by Stride Capital in March 2026, following a $28.5M Series A in 2023.
Space technology company developing orbital mechanics software and systems for satellite mission planning and operations.
R&D company in robotics, machine learning, and sensing; NASA TechLeap winner developing the Saiph intersection-safety system.
Software platform helping orthodontic practices manage insurance, patient onboarding, billing, and collections — powering thousands of practices nationwide.
Autonomous, electric yard-truck operations for logistics distribution centers — backed by NEA and Koch Disruptive Technologies.
Outdoor and active lifestyle media company operating Outside magazine, Trailforks, and a portfolio of outdoor brands and platforms.
AI-powered platform delivering intelligent automation and insights for business operations.
Workforce development platform using behavioral assessments and learning pathways to connect people with careers aligned to their strengths.
Supply chain intelligence and insurance platform using IoT sensors and data analytics to protect sensitive goods in transit.
AI-powered party and event planning platform helping hosts create personalized menus and celebration experiences.
Develops autonomous robots and software (Pathfinder, Pulse OS, Co-Pilot) for airport ground operations — automating baggage and cargo movement on airport tarmacs.
Cloud commerce marketplace enabling Managed Service Providers (MSPs) to buy, sell, bill, and manage cloud products across hundreds of vendors. Founded by John Street; one of Denver's largest tech unicorns with ~$2B revenue.
Agentic banking platform enabling banks to deploy AI agents that translate natural language intent into validated financial workflows and autonomous money movement.
Industrializing sodium-ion battery storage to expedite the shift to renewable energy with safer, lower-cost grid-scale stationary batteries.
Peaksware is a performance software company whose flagship product TrainingPeaks is used by professional cycling teams, Olympians, and hundreds of thousands of endurance coaches and athletes to plan, track, and analyze training. The company also owns TrainHeroic, MakeMusic, Alfred Music, and Fons studio management software.
Pebl (formerly Velocity Global) operates an AI-first global Employer of Record (EOR) platform enabling companies to hire, pay, and manage talent across more than 185 countries. Its technology combines compliance, payroll, and benefits administration for distributed workforces.
Carbon sequestration company developing soil carbon measurement and credit generation solutions for agricultural land.
Robotics software company built on the open-source MoveIt motion planning framework, serving industrial and aerospace robotics customers.
Real-time player recruitment app for recreational and pickup sports, built to keep the "sandlot mentality" alive. Players can organize games, find nearby players, manage RSVPs, and fill open spots across sports like soccer, basketball, pickleball, and flag football. Operated by Kinesthete, LLC.
Pie Insurance is an insurtech focused on workers' compensation coverage for small businesses. The company uses data and technology to deliver instant online quotes and streamlined underwriting for an underserved SMB segment.
AI-native human capital services platform modernizing talent acquisition and workforce management for enterprises.
Enterprise identity and access management platform for SSO, MFA, and identity federation. Taken private by Thoma Bravo in 2022 for ~$2.8B.
Advanced-recycling company using a proprietary plasma platform to convert mixed waste plastic into next-generation energy materials — enriched graphene, low-carbon ammonia, and industrial carbon products.
Plume is a telehealth platform delivering gender-affirming care to the transgender and non-binary community across the United States via an app-based subscription model. Co-founded by Stanford-trained physician Matthew Wetschler and Jerrica Kirkley, the company is an Endeavor Colorado portfolio company.
Maker of high-strength, 3D-printed titanium prosthetic fingers (the Point Digit) for people with partial-hand amputations; spun out of CU Boulder and acquired by Hanger, Inc. in 2025.
CU Boulder spinout developing ferroelectric electro-optic materials and ultra-high-bandwidth, low-power optical modulators for data center, HPC, and AI interconnects. Raised a $10M Series A in August 2025 led by Koch Disruptive Technologies.
Clinical-stage immunology company developing a new class of anti-IgE antibody therapies (lead program PHB-050) for atopic conditions such as food allergy, allergic asthma, and atopic dermatitis.
Household payroll and tax compliance service making it easy for families to legally pay nannies, housekeepers, and other domestic workers.
Data integration and analytics platform enabling non-technical users to connect, analyze, and act on data from any source.
Manufacturer of recycled rubber safety barriers made from waste (scrap) tires, producing high-density barriers for roadways, construction sites, and event venues while diverting tires from landfills.
Project Canary is a climate-tech SaaS and sensor company providing continuous methane emissions monitoring, measurement, and ESG data for the energy value chain. Co-founder Chris Romer transitioned to Chairman, with Will Foiles serving as CEO. The company has raised $111M to scale its emissions measurement solutions.
Bio-cement startup using algae-derived calcium carbonate to bind concrete blocks, dramatically reducing cement's carbon footprint. CU Boulder spinout.
Developer of Transwing VTOL unmanned aircraft whose wings fold to transition between vertical and fixed-wing flight, used for U.S. Navy ship-to-shore cargo logistics. Holds Navy/DIU contracts worth up to $12M and received a strategic growth investment from ONE Bow River National Defense Fund in May 2026.
Space Traffic Management company using the Atmosphere-As-A-Sensor to maintain custody of high speed objects transiting the near Earth region.
Modern data-analysis platform that combines spreadsheet functionality with AI, Python/SQL, and database connections in a single canvas.
World-leading quantum computing company combining trapped-ion hardware with a full quantum software stack. Completed its Nasdaq IPO in June 2026 (ticker QNT), raising $1.68B at roughly a $15.6B valuation. Formed in 2021 from the merger of Honeywell Quantum Solutions and Cambridge Quantum. Major Broomfield, CO headquarters and engineering presence.
Continuous product design platform that uses ML to surface user friction in real time across web and mobile. A unicorn since 2021, founded by Mario Ciabarra.
Builds automated satellite mission management and mission control software for commercial and government constellation operators, founded by former OneWeb engineers. Raised an $18M Series A led by Washington Harbour in November 2025 to open a classified mission operations center in the Denver area.
Builds compact optically pumped magnetometers (OPMs) that enable wearable magnetoencephalography (MEG) brain imaging without cryogenic cooling. Bootstrapped to profitability on NIH SBIR grants and product sales rather than venture capital.
Building the WindRunner, the world's largest aircraft, designed to deliver giant onshore wind turbine blades — unlocking cheaper green electricity at scale.
RADICL provides Cybersecurity-as-a-Service via an autonomous virtual SOC purpose-built for SMBs supporting U.S. critical infrastructure and the Defense Industrial Base. Co-founded by LogRhythm co-founder Chris Petersen, the company secured $31M in Series A funding in early 2026.
Video game company building the 'Unioverse,' a community-owned, royalty-free game franchise and shared IP/asset layer with blockchain-enabled ownership, partnering with studios to ship multiple titles.
NIST top-ranked AI facial-recognition and biometric-verification software for government, defense, and commercial use.
Aerospace 3D-printing company whose patented Microwave Assisted Deposition (MAD) technology rapidly manufactures aerospace-grade thermoset and ceramic composites for hypersonics, propulsion, reentry vehicles, satellites, and rockets. Relocating its HQ and manufacturing to Broomfield, CO.
Subscription billing and revenue management platform serving thousands of SaaS, media, and consumer subscription businesses globally.
Managed Detection and Response (MDR) provider delivering threat intelligence, endpoint security, and incident response with industry-leading SOC operations.
Space infrastructure company manufacturing solar arrays, deployable structures, and on-orbit manufacturing technologies. Significant Longmont engineering presence.
Space robotics company developing self-assembling, reconfigurable in-orbit structures using patented TESSERAE technology — flat-packed tiles that autonomously dock and reconfigure via electromagnetic formation flying to build scalable space infrastructure.
Automates clinical-trial communication between research institutions and patients to streamline recruitment and engagement.
Market intelligence and advisory firm for deep-tech decision-makers, serving the quantum, AI, space, climate, and digital twin sectors.
Biopharmaceutical company developing disease-modifying therapies for rheumatoid arthritis and autoimmune conditions.
AI-powered real estate platform that lets homeowners list and sell their homes without paying traditional agent commissions, offering AI pricing guidance, MLS/Zillow distribution, document prep, and concierge support.
Riot Platforms is a vertically integrated Bitcoin mining and digital infrastructure operator running large-scale mining facilities in Texas and providing engineering services for data center construction. Originally incorporated as Bioptix in 2000; pivoted to Bitcoin mining and rebranded as Riot Platforms in 2017.
B2B tech-enabled services company that helps better-for-you consumer packaged goods brands grow in retail, combining sales management with AI-enabled tools for market analysis, retail launch planning, and distribution.
Provides crypto-backed consumer and commercial loans, letting borrowers use Bitcoin and other digital assets as collateral; operates in 44 states and seven countries. Raised a $64.4M recapitalization in February 2023 to resume full operations after the FTX-era freeze.
Driver risk-management SaaS with continuous MVR monitoring and insurance underwriting tools used by fleets and insurers nationwide.
Creator of the Scaled Agile Framework (SAFe), providing enterprise agility training, certification, and software.
ScaleIP (formerly LicenseLead) is an AI-powered IP commercialization platform whose ARIA assistant analyzes global patent data to help universities, technology transfer offices, government labs, and corporations identify licensees and close IP deals faster. Customers include Los Alamos National Laboratory, CU Anschutz, and Dana-Farber. CEO Dillon Eldridge was appointed in 2025.
Software platform for higher-education faculty affairs, streamlining faculty workflows for colleges and universities. Colorado-headquartered and backed by lead investor Range Ventures.
AI-enabled operating system built exclusively for liquor and alcohol-beverage retailers, combining point-of-sale, payments, inventory, invoice reconciliation, and pricing intelligence in one cloud-native platform.
Autonomous, electric commercial lawn mower (the M.52) for landscaping companies — founded by iRobot and Sphero alumni.
Searchcraft is an AI-native, drop-in semantic search engine built in Rust and designed for front-end developers, delivering sub-millisecond responses across hundreds of millions of records. The product combines keyword precision with semantic intent detection without relying on vector databases or opaque ranking models.
Provider of carrier-grade, self-protecting DNS software and Protective DNS services that block malicious domains, malware, and phishing for telecom and government networks serving over 1.5 billion subscribers.
AI-assisted palliative care platform helping patients with serious illnesses and their providers coordinate care transitions through virtual consultations, real-time communication, and automated care-management triggers.
Commercial space company building the Dream Chaser spaceplane and the LIFE commercial space station module. Spun out of Sierra Nevada Corporation.
Telecom SaaS company whose patented CORA Mobile Edge on-device content-shaping technology compresses data-intensive video to cut mobile data and bandwidth costs for network operators and consumers.
Enterprise Web3 customer-engagement and loyalty SaaS platform enabling brands, banks and sports organizations to run branded wallet, points and NFT-based activations; partners include the NBA, PepsiCo, Visa, Unilever, Accenture and WPP.
Product intelligence platform providing retailers and brands with regulatory, sustainability, and compliance data for consumer products.
Autism therapy provider delivering naturalistic ABA therapy in child-friendly centers designed to help kids thrive socially and developmentally.
Develops all-solid-state batteries for electric vehicles and aviation — partnered with Ford and BMW. Publicly traded on Nasdaq (SLDP).
Insurance-covered behavioral-health marketplace matching patients with therapists and psychiatrists, in person or virtually. Reached unicorn status in 2021.
Soona is a virtual content creation platform for e-commerce brands, delivering professional photography, video, and AI-generated product imagery with 24-hour turnaround. Co-founded by Liz Giorgi, the company has acquired Trend.io and Mokker.ai to expand its creator network and generative AI capabilities.
Waste sorting and recycling technology company using AI and computer vision to improve material recovery at scale.
Immersive audio and VR entertainment company creating spatial sound experiences for live events and digital platforms.
Sovrn is a publisher technology company that helps thousands of online publishers maximize revenue through an ad exchange, programmatic advertising tools, affiliate commerce software, and data analytics. Reaching over 500 million consumers across 40 billion pageviews daily, Sovrn gives independent publishers the infrastructure to compete with large media platforms.
Spaxial is a Spatial Foundation Model purpose-built for 3D scene understanding, enabling game engines and 3D applications to analyze, assemble, and optimize entire 3D environments through reasoning about objects and their relationships. The platform offers native Unity editor integration with Unreal Engine support in development, serving game development, VR/AR, architectural visualization, and simulation training.
Makes purpose-built enterprise wireless communication devices — Wi-Fi and DECT handsets and rugged smartphones — plus device management software for healthcare, retail, and manufacturing frontline workers. Owned by Sun Capital Partners since 2012 and headquartered in Boulder.
Just-in-time sales enablement platform unifying content management and AI to deliver in-the-moment guidance to revenue teams in their flow of work.
Originally famous for app-controlled robotic balls and the Star Wars BB-8; now focused on STEAM education robotics products for K-12 schools.
AI-powered animation studio from the JibJab and StoryBots founders, building original film, TV, games, and toy franchises.
Denver-based veterinary care company operating physical clinics that provide primary, urgent, and emergency pet care with extended daily hours across the Denver metro, Chicago, Colorado Springs, and Salt Lake City.
Connected-mobility startup building Vehicle-to-Everything (V2X) technology that links vehicles in real time with other vehicles, road users, and smart-city infrastructure to improve road safety.
Supplies frequency-stabilized laser systems, Fabry-Perot cavities, and related hardware for research, quantum information, and precision timing. Independent and privately held.
Hyperscale data-center developer and operator delivering colocation, build-to-suit, and powered-shell digital-infrastructure solutions across North America.
API and application security testing platform that runs in CI/CD to detect and resolve vulnerabilities before code reaches production.
Developing a planned 53-acre space readiness and innovation campus in Lone Tree — billed as the world's first publicly accessible spaceflight training facility — with astronaut training, R&D facilities, and a roughly $120M academy.
Manufactures composite-overwrapped pressure vessels for hydrogen storage, CNG, and hydraulic accumulators, serving clean energy, transportation, and aerospace markets. Raised a $15M round in August 2024 to scale hydrogen storage production (about $57.5M raised total).
Distributed multi-cloud identity orchestration platform for hybrid and multi-cloud environments — “the identity fabric” for modern enterprises.
Service-Disabled Veteran-Owned small business developing autonomous ground vehicles and robotic systems for defense and commercial logistics, including unmanned cargo movement and robotic refueling. Funded largely through U.S. Air Force, Marine Corps, and other DoD contracts.
Enterprise-grade chat API and in-app messaging platform providing scalable real-time communication infrastructure for social networks, activity feeds, and messaging apps.
Value-based kidney care platform combining tech-enabled care delivery with value-based payer contracts. Raised $550M in 2025; serves 145,000+ patients.
Intelligent cloud-based post-production platform making media workflows accessible to dispersed and hybrid creative teams without requiring file downloads or syncing.
Mobile game studio developing narrative-driven and social games with strong community followings.
Smart lawn care platform delivering personalized, science-based lawn and garden products directly to homeowners.
Femtech company offering affordable, sustainable period care products and reproductive health resources.
SaaS platform enabling enterprise governance and management of any GenAI solution — visibility, policy enforcement, and DLP across LLM use.
Low-code security automation, orchestration, and AI-SOC platform that lets enterprise SOCs automate detection, response, and case management.
Syght builds passive millimeter-wave imaging sensors paired with AI-driven automatic threat recognition to detect concealed weapons, explosives, and contraband on moving subjects at a distance. The non-ionizing technology operates through clothing, luggage, fog, and darkness without producing invasive imagery, with applications spanning security checkpoints and retail loss prevention.
Manufacturer of jet-engine-based mobile fire-suppression units (the 'Hurricane' and 'Storm Cell') that rapidly deliver wind, water/mist and fire retardant to deny and contain wildfires, harden evacuation routes, and protect structures.
Field service management platform streamlining work order management, scheduling, and asset maintenance for facilities teams.
Construction-robotics startup developing autonomous robots (concrete grinders/polishers) that automate the grinding and polishing of large concrete floor areas to improve construction speed, precision, and productivity.
Designs and manufactures large deployable antennas and deployable structures for smallsats and national security space missions. Self-funded with over 145 employees; in 2025 it opened a purpose-built 120,000 sq ft manufacturing facility in Louisville to scale antenna production.
Legal-tech platform that brings transparency to contract review, pre-rating standard agreements so businesses can sign faster with less back-and-forth.
Business text messaging platform for recruiting, sales, and customer service teams, integrating with major CRM and ATS systems. Has raised about $28.5M total, including a $22M Series C in December 2021 led by Eastside Partners.
Online marketplace for buying and selling premium used cycling gear. Closed October 2024 and relaunched under new ownership (Elshair Companies) in November 2024.
Synthetic biology company developing small-molecule therapeutics against historically undruggable proteins using microbial systems for drug discovery.
Builds X-ray scanning and on-orbit inspection systems plus large-aperture orbital platforms for in-space services and manufacturing.
AI platform for the wealth management industry, building a portfolio of consumer and B2B fintech apps. Founded by Vinay Nair.
Tilled provides PayFac-as-a-Service, enabling software companies to embed payment processing for their customers without becoming a registered payment facilitator. Founded by Caleb Avery, the company has raised nearly $40M total and reported over 500% YoY growth in 2024.
Third-party leave administration software simplifying FMLA, parental, and disability leave management for employers through technology and people-first service.
Todyl is a cloud-first cybersecurity platform that unifies SASE, endpoint security, SIEM, MXDR, and GRC into a single-agent solution for MSPs and businesses. The platform enables organizations to manage threat prevention, detection, and response alongside governance and compliance from one integrated system.
Develops master-planned data-center campuses and land for hyperscale megasites.
Carbon dioxide removal company that co-produces sulfuric acid and green hydrogen while enabling sustainable critical-element production.
Trimble provides technology solutions across construction, geospatial, agriculture, and transportation, connecting the physical and digital worlds through positioning, modeling, and analytics software. The company relocated its global headquarters from Sunnyvale, CA to Westminster, CO in 2022.
Builds spacecraft and space-domain mission software for Space Force superiority missions — most recently raised $650M at a $2.2B valuation.
Tynt develops Reversible Metal Electrodeposition (RME) technology that enables dynamic dimming across transparent surfaces, from smart eyewear and AR lenses to building windows. The platform achieves an industry-leading 0.01% to 90% visible light transmission range with low haze, switching from clear to black in under 10 seconds. Co-founder and CEO Tyler Hernandez developed the core technology during his PhD at Stanford.
Launch services provider operating the Vulcan Centaur rocket (and previously Atlas V and Delta IV) for national security, civil, and commercial missions. A 50/50 joint venture of Boeing and Lockheed Martin with roughly 2,500-3,000 employees.
Technology partner of energy providers transitioning to clean energy, offering an AI- and SaaS-driven platform serving 85+ utilities representing 110M+ energy customers and managing 8.5+ GW of flexible load. In March 2026, Octopus Energy Group acquired a majority stake; Schneider Electric remains a minority partner.
Urban Sky develops reusable stratospheric microballoons that capture high-resolution aerial imagery and persistent monitoring data at a fraction of satellite costs. Applications include real-time wildfire monitoring, mapping, and defense ISR. The company raised $30M Series B in February 2025.
Independent rocket-propulsion manufacturer producing the Hadley and Ripley liquid engines and solid rocket motors for space, hypersonic, and missile defense.
Vantage Data Centers develops, owns, and operates hyperscale data center campuses across North America, EMEA, and APAC, serving cloud and AI customers. In 2024 the company secured a record $13 billion in incremental funding to support expansion driven by AI and cloud adoption.
Carbon fiber recycling company producing recycled carbon fiber for thermoplastic compounding and thermoset applications. Closed an oversubscribed $10M preferred equity round in January 2024 led by Diamond Edge Ventures, and moved into a new Denver manufacturing headquarters with roughly 10x the capacity.
Tech-enabled last-mile delivery network providing e-commerce brands with fast, flexible, and customer-centric parcel delivery.
AI-driven B2B price optimization and commercial-excellence platform for large enterprises — backed by Francisco Partners.
Founded in 1996, an electronics design and manufacturing partner operating from a Colorado facility certified to ISO 9001, ISO 13485, and AS9100D. Serves the medical, measurement and controls, aerospace, and defense markets with end-to-end solutions including PCB assembly, final product assembly, system integration, configure-to-order customization, warranty and repair, and order fulfillment.
Vero Networks designs, builds, and operates fiber infrastructure serving residential customers, schools, enterprises, government entities, and wireless carriers across the United States. The company offers dark fiber, lit fiber, private networks, and broadband internet through a growing portfolio of regional operating brands.
Insurance technology leader providing SaaS solutions that automate workflows for carriers, brokers, and MGAs. Acquired by Roper Technologies in 2020.
Designs and manufactures frequency combs, lasers, and precision laser-control electronics for quantum timing, computing, networking, and sensing. In March 2024 it closed a $5M Series Seed round led by Corporate Fuel with participation from Caruso Ventures.
Operates one of the world's largest aerial-imagery programs with ML-based property and building-attribute extraction.
VieCure is an AI-powered oncology platform that provides clinical decision support and precision medicine tools to help cancer care providers personalize treatment plans. The platform integrates evidence-based protocols, telemedicine, and patient monitoring to democratize access to high-caliber cancer care.
Virtual care platform that reverses type 2 diabetes and treats metabolic conditions through nutrition science and continuous physician support.
Builds load stabilization systems that stop spin and sway on helicopter hoists and crane loads, including the Army airworthiness-qualified Vita Rescue System and the Vita Load Navigator for construction. Has raised more than $75M total, most recently a $44M debt financing in January 2024.
Vorto is an AI-enabled autonomous supply chain platform that automates demand, procurement, logistics, and operations for shippers and carriers. Founded by Priyesh Ranjan to transform the trucking supply chain, the company is backed by Golden Gate Capital.
Defense and space technology company developing solutions for national security and commercial space operations — publicly traded on NYSE.
Watchmaker Genomics develops high-performance enzymes for next-generation sequencing and genomic research, using a computational design and directed evolution platform. Co-founded by Trey Foskett (formerly Kapa Biosystems, sold to Roche for $500M), the company is an Endeavor Colorado portfolio company.
Cloud-based endpoint protection with real-time threat intelligence; acquired by OpenText in 2019 and now part of OpenText Cybersecurity.
Consumer-first healthcare technology turning eligibility into participation through personalized, AI-driven engagement for underserved communities.
Live-streaming and video infrastructure with deployable software and cloud streaming services trusted by tens of thousands of customers worldwide.
Vehicle wrap marketplace connecting businesses with vetted installers for fleet graphics, vinyl wraps, and branded vehicle design.
Commercial solar financing platform aggregating investor capital to fund small- and mid-scale solar installations.
Developing commercial laser inertial fusion energy using low-cost electron-beam-pumped excimer lasers; raised a $100M Series A in June 2024 led by Hedosophia with Breakthrough Energy Ventures and Lowercarbon Capital, over $150M total. In June 2026 the DOE approved its Athena fusion power plant preconceptual design milestone.
Publicly traded aerospace company (Nasdaq: XTIA) that spent a decade developing the TriFan 600 VTOL business aircraft before pivoting in 2026 to focus on the commercial drone market through its Drone Nerds acquisition. Reported $27.7M revenue in Q1 2026.
Manufacturer of standardized small-satellite buses and turnkey spacecraft missions, a major supplier to the Space Development Agency's Transport Layer. Went public on the NYSE in January 2026, raising $629M at a valuation over $4 billion, and has since acquired ATLAS Space Operations and Solestial.
Bandwidth and fiber-infrastructure provider operating networks across 300+ U.S. and European markets. Owned by DigitalBridge/EQT.
High-performance, multiplayer code editor built in Rust for collaborative development with AI agents, designed for speed-of-thought coding.
Developer of next-generation location-based GPS and AR mapping solutions for outdoor recreation, defense, and autonomous systems.
Digital-first platform for home electrification, specializing in heat pump and electrification design and project management for homeowners and contractors.